Tribestan (Tribulus) The Original Tribulus

Tribestan® (Tribulus)

Further R&D efforts included incorporation in a tablet form of a substance greatly affected by absorbed humidity. Tribestan was approved for production and implemented in mainstream practice in 1985, and on the market ever since. The product is practically non-toxic and has no side effects - no changes of lifestyle required when accepting Tribestan. Tribestan is natural and safe. Tribestan is based on a proprietary extract from Sopharma and the active substance does not contain herbal particles.

Tribestan is a completely natural non-hormonal herbal product derived from the plant Tribulus terrestris L., Bulgaricum, which contains predominantly saponins of furostanol type (not less than 45% in Tribestan), with prevailing quantity of protodioscin. Over 25 years of experience with natural herbal Tribestan administration has seen no toxicity and negative effects to date.



Tribestan

PROPERTIES AND APPLICATIONS

  • May be used by recreational athletes.
  • Traditionally used as a natural supplement.
  • Tribestan is indicated for use as a single agent or as a component in complex therapies.

TRIBESTAN'S SAFETY

  • Special attention should be given to the harmlessness of the natural herbal product Tribestan.
  • No evidence of acute, sub-acute and chronic toxicity has been found during the experimental behavioral, hematological, functional, biochemical and morphological studies.
  • Absence of carcinogenic and teratogenic effect.
  • No adverse effects were noted in any of the clinical studies and additional research demonstrated no adverse effects.

A GIFT OF NATURE TO HUMANITY!

-- Margarita Tomova, Ph.D. --

THE HEAD OF THE DEVELOPMENT TEAM CALLED TRIBESTAN

Tribestan is a natural product and is obtained from the thorn plant Tribulus Terrestris L., growing in Bulgaria. The natural habitats of the plant have been extensively studied and are well defined as species and like other plants, would often change its composition depending on the site and conditions of growth. The cultured plant is already being used in Bulgaria as well. Cultivation is a complicated process because of the specificity of the plant. Tribestan has well defined chemical composition and is standardized in relation to its active ingredients. It is administered orally as tablets of 250 mg. Its dosage quantities and intake duration vary with the mildness or severity of the case. The author and the product development team took very active part in its implementation in regular production by the manufacturer Sopharma AD of Sofia, Bulgaria. Curiously enough, the development of this product cost nearly 20 years to the principal author and the research team, as the active ingredients turned out to constitute a new type of active substances. Thus, an author's hypothesis, connected with the long-lived experience was finally crowned with success and got its modern tune and meaning.

Margarita Tomova, Pharm. D., Assoc. Prof. has been a long standing director of the Natural Steroids Laboratory with the Phytochemistry Division of the Chemical Pharmaceutical Research Institute of Pharmachim in Sofia, Bulgaria. Her chief area of research interest was natural substances of plant origin, where she has published over 60 research papers in Bulgaria and Germany. She has also delivered large number of lectures and reports at various scientific forums in Bulgaria and abroad (Russia, Germany, Czech Republic, Sweden, Switzerland, Italy, etc.). As an experienced Head of Laboratory she has trained and virtually created many young scientists, and has further reviewed and guided their professional career, promoting them and helping them achieve higher degrees and ranks. She is a life member of the Union of Scientists in Bulgaria, the Union of Bulgarian Pharmacists, member of the Scientific Board of the Institute of Botany, the Bulgarian Academy of Sciences, member of the Scientific Board of the Chemical Pharmaceutical Research Institute, etc. She has received number of honorary diplomas, certificates of recognition and awards. She is the author of number of licensed preparations of plant origin.

Tribestan

Tribestan has been used in recreational sports!

Tribestan is a completely natural non-hormonal herbal product derived from the plant Tribulus terrestris L., Bulgaricum, which contains predominantly saponins of furostanol type (not less than 45% in Tribestan), with prevailing quantity of protodioscin. Over 25 years of experience with natural herbal Tribestan administration has seen no toxicity and negative effects to date.

We would like to emphasize that the push towards higher Protodioscin content in Tribulus based products is misleading. The product claiming higher levels of Protodioscin simply use inferior extracts or ground herbal material and artificially add Protodioscin. The true superiority of the effectiveness and safety of Tribestan is expressed in a biologically balanced substance where are present not only Protodioscin, Protogracillin, but other key saponins in critically important ratios.

Tribestan has been used with no contraindications, no toxicity and no side effects. With its good safety profile and its natural herbal origin, Tribestan is sold as a dietary supplement in many countries with little restriction on its use.

Special attention should be given to the harmlessness of the natural herbal product Tribestan. No evidence of acute, sub-acute and chronic toxicity has been found during the experimental behavioral, hematological, functional, biochemical and morphological studies. Absence of carcinogenic and teratogenic effect. No adverse effects were noted in any of the clinical studies and additional research demonstrated no adverse effects.

Application Guidelines

Tribestan is an oral non-hormonal phytochemical product.

Composition

One tablet contains 250 mg Tribulus terrestris L. Bulgaricum extract.

Indications

Traditionally used as a dietary supplement. Has been reported to have beneficial effects for men and women.

DOSAGE

  • Most common use: 1 tablet 3 times daily during meals. 2 tablets for over 100 kg (220 lbs) body weight.
  • For adults: 2 tablets 3 times daily during meals for 40 to 50 days. Maintenance dose: One tablet 1 to 3 times daily. Quantity needed for complete course is 3 retail units of 60 tablets each.
  • For enhanced effect: 2 tablets 3 times daily during meals for 90 days. If necessary, repeat after an interval of several weeks.

Toxicity, Side Effects, Adverse Effects and Contraindications

None reported.

Special Usage Instructions and Warnings

The administration of Tribestan to children and to pregnant or lactating women is not recommended.

Overdose

Active charcoal and gastric lavage are initiated in case of overdose.

Form and packaging

Tablets of 250 mg in retail package of 60 tablets.

Formulation and Active Substance Content

Tribestan is an original non-hormonal preparation of plant origin. Its active components are saponins of furostanol type isolated from the epigeous part of the Tribulus terrestris L. plant. The preparation has been standardized on a base of the predominating compound furostanol saponins 45% with predominating quantity of protodioscine.

Dosage and Mode of Application

The dosage and duration of intake are being determined individually. Most often, the dose is 1 - 2 tablets of 250 mg 3 times a day with meals. The duration in some cases should be at least 40 - 50 days.

The necessary minimal therapeutic cycle to be 80 – 90 days.

The treatment is strictly individually adjusted and depends upon the severity of the condition. The usual dose is 1 - 2 tablets of 250 mg 3 times a day with meals. The combined administration of Tribestan with other preparations is recommended in some cases.

Use during Pregnancy or Lactation

The animal experiments showed that Tribestan possesses a very low toxicity. No evidence of any carcinogenic, embryotoxic and/or teratogenic effect was found. However, the preparation must be discontinued whenever a pregnancy is established.

Cautions and Specific Warnings

The transition from the effect-achieving to the maintenance dose must be gradually realized. The abrupt reduction of the dose that achieved the effect results in a renewed triggering of the whole complex of signs and symptoms.

Regimen 1

Tribestan is usually recommended in a dose of 2 tablets 3 times per day for 20 days. Thereafter, the dose is being reduced by 1 tablet every 4 - 5 days to reach maintenance dose of 1 tablet 2 times a day whereas the term of treatment depends upon the achieved effect.

Regimen 2

Alternatively, Tribestan may also be administered in a dose of 2 tablets 2 times per day for a 30-day course with a following dose reduction to 1 tablet 2 times daily every 4 - 5 days.

Regimen 3

Tribestan may be administered in a dose of 1 tablet 3 times a day continuously for a longer period of time (up to one year).

Please note that Sopharma does not endorse the usage recommendation, practices, opinions, etc. as they have been developed from empirical experience.

Tribestan has been on the market for over 30 years.

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