Tribestan (Tribulus) Application Guidelines



Tribestan is an oral non-hormonal phytochemical biostimulator with active ingredient derived from Bulgarian Tribulus terrestris L., a proprietary extract from Sopharma Plc.

Tribestan composition: One tablet contains 250 mg Tribulus terrestris L. Bulgaricum extract.

Tribestan indications: Traditionally used as a dietary supplement with its impecable safety profile, pratically non-toxic and no side effects.

Tribestan dosage: 1 tablet 3 times daily during meals. Two tablets for over 100 kg (220 lbs) body weight. For adults: 2 tablets 3 times daily during meals for 40 to 50 days. Maintenance dose: 1 tablet 1 to 3 times daily. Quantity needed for a complete course is 3 to 5 units of 60 tablets. For extra effect 2 tablets 3 times daily during meals for 90 days. If necessary, repeat after an interval of several weeks.

Toxicity, Side Effects, Adverse Effects and Contraindications: None reported.

Special Usage Instructions and Warnings: The administration of Tribestan to children and to pregnant or lactating women is not recommended.

Overdose: Active charcoal and gastric lavage are initiated in case of overdose.

Retail form and packaging: Tablets of 250 mg in retail package of 60 tablets. Shipper box of 12 retail packages. A case of 144 retail packages of Tribestan.

Formulation and Active Substance Content: Tribestan is an original non-hormonal preparation of plant origin. Its active components are steroid saponins of furostanol type isolated from the epigeous part of the Tribulus terrestris L. plant. The preparation has been standardized on a base of the predominating compound protodioscine.

Dosage and Mode of Application

In men: The dosage and duration of treatment are being determined individually. Most often, the dose is 1 - 2 tablets of 250 mg 3 times a day with meals. The duration of the therapy in some cases should be at least 40 - 50 days.

In women: The treatment is strictly individually adjusted and depends upon the severity of the condition. The usual dose is 1 - 2 tablets of 250 mg 3 times a day with meals.

Use during Pregnancy or Lactation: The animal experiments showed that Tribestan possesses a very low toxicity. No evidence of any carcinogenic, embryotoxic and/or teratogenic effect was found. However, the preparation must be discontinued whenever a pregnancy is established.

Cautions and Specific Warnings: In treatment of women the transition from the effect-achieving to the maintenance dose must be gradually realized. The abrupt reduction of the dose that achieved the effect results in a renewed triggering of the whole complex of signs and symptoms.

Regimen 1

Tribestan is usually prescribed in a dose of 2 tablets 3 times per day for 20 days. Thereafter, the dose is being reduced by 1 tablet every 4 - 5 days to reach maintenance dose of 1 tablet 2 times a day whereas the term of treatment depends upon the achieved effect.

Regimen 2

Alternatively, Tribestan may also be administered in a dose of 2 tablets 2 times per day for a 30-day course with a following dose reduction to 1 tablet 2 times daily every 4 - 5 days.

Regimen 3

Tribestan may be administered in a dose of 1 tablet 3 times a day continuously for a longer period of time (up to one year).

Use in sports: Tribestan has gained significant popularity in bodybuilding and recreational sport.


Why Tribestan and NOT other Tribulus products?

The active substance in Tribestan is a proprietary extract of Tribulus Terrestris and does NOT contain herbal particles that may pose health danger.

Further R&D efforts included incorporation in a tablet form of a substance greatly affected by absorbed humidity. Tribestan was approved for production and implemented in mainstream practice in 1985, and on the market ever since. The product is practically non-toxic and has no side effects - no changes of lifestyle required when accepting Tribestan. Tribestan is natural and safe. Tribestan is based on a proprietary extract from Sopharma and the active substance does not contain herbal particles.

Tribestan shipper box

Properties and applications

  • May be used by recreational athletes.
  • Traditionally used as a natural supplement.
  • Tribestan is indicated for use as a single agent or as a component in complex therapies.

Tribestan's safety

Tribestan has been used with no contraindications, no toxicity and no side effects. With its good safety profile and its natural herbal origin, Tribestan is sold as a dietary supplement in many countries with little restriction on its use.

  • Special attention should be given to the harmlessness of the natural herbal product Tribestan.
  • No evidence of acute, sub-acute and chronic toxicity has been found during the experimental behavioral, hematological, functional, biochemical and morphological studies.
  • Absence of carcinogenic and teratogenic effect.
  • No adverse effects were noted in any of the clinical studies and additional research demonstrated no adverse effects.
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